It occurs in patients of all ethnic groups, but in the united states, it is more commonly seen in darkskinned individuals. Actinic reticuloid imitating sezary syndrome article pdf available in acta dermatovenerologica alpina, panonica, et adriatica 2. A case of chronic actinic dermatitis that responded. Disseminated superficial actinic prokeratosis icd10cm diagnosis code l56. Chronic actinic dermatitis cad is persistent light reactivity encompassing actinic reticuloid and photosensitive eczema. In the eye, the cornea, in particular, but also the lens and retina are most.
Demonstration of clonal t cell receptor tcr gene rearrangements has been suggested as a potential diagnostic criterion, but the results obtained thus far have been conflicting. Differentiation between actinic reticuloid and cutaneous t. Actinic reticuloid, international journal of dermatology 10. Differentiation between actinic reticuloid and cutaneous t cell. Light testing with a monochromator showed abnormal photosensitivity to both short and longwave ultraviolet light as well as to the violet, blue, and green wavelengths of visible light. Actinic keratosis is seen in fairskinned persons on skin areas that have had longterm sun exposure. C 811 cryosurgery is an effective modality for treating solitary or multiple actinic keratoses. We report four cases of actinic reticuloid, including the first case ever reported in a woman. We have concluded that not all the patients are persistent light reactors and that the histologic presentation can be quite variable, in some. Perelman department of dermatology, new york university abstract.
To update readers on the current understandings of chronic actinic dermatitis cad in regard to epidemiology, clinical findings, pathophysiology, treatment, and prognosis. Arch dermatol 1995 actinic reticuloid is a chronic photosensitivity dermatosis that can lead to erythroderma. Sep 11, 2012 chronic actinic dermatitis is a condition involving abnormal cutaneous photosensitivity to uv and, often, visible wavelengths. Chronic actinic dermatitis associated with adult tcell. Pdf actinic reticuloid ar or chronic actinic dermatitis is considered a sunlight induced pseudolymphoma psl on.
It is rare, but more common in the elderly than in younger populations, with an estimated prevalence of one in 2000 in the. Chronic actinic dermatitisactinic reticuloid cadar is an eczematous hypersensitivity reaction to ultraviolet rays that can vary from mild eczematous cases to ar, the most severe cases which. It is characterised by severely itchy, red, inflamed, and thickened dry skin, mainly in areas that have been exposed to sunlight or artificial light. Actinic keratoses should be treated because of their potential to progress to squamous cell carcinomas. Actinic reticuloid with transition to photosensitive eczema and return to actinic reticuloid serrano. Pdf file of the complete article 242k, or click on a page image below to browse page by page.
Chronic actinic dermatitis also known as actinic reticuloid, chronic photosensitivity dermatitis, persistent light reactivity, and photosensitive eczema. It is considered precancerous or an early form of cutaneous squamous cell carcinoma a keratinocyte cancer. Jan 23, 2020 actinic keratosis ak is a uv lightinduced lesion of the skin that may progress to invasive squamous cell carcinoma. Actinic keratosis is often treated with either cryotherapy or topical creams or gels. Actinic reticuloid with transition to photosensitive eczema and return to actinic reticuloid serrano sanmiguel g, bonillo. Chronic actinic dermatitis actinic reticuloid cadar is an eczematous hypersensitivity reaction to ultraviolet rays that can vary from mild eczematous cases to ar, the most severe cases which may resemble cutaneous tcell lymphoma. Arch dermatol 1994 chronic actinic dermatitis cad is an idiopathic photosensitivity characterized by an eczematous photoeruption, a lowered minimal erythema dose to uvb radiation, and histologic findings of.
Chronic actinic dermatitis cad, one of the immune mediated photodermatoses, comprises a spectrum of conditions including persistent light reactivity, photosensitive eczema and actinic reticuloid. Chronic actinic dermatitis a study of clinical features. What is chronic actinic dermatitis chronic actinic dermatitis is a rare skin condition that mainly affects men over the age of 50 years. But because this risk is low, treatments are generally aimed at avoiding scars or other disfiguring marks as much as possible. Actinic reticuloid is a rare chronic idiopathic photosensitive dermatosis belonging to the spectrum of chronic actinic dermatitis and may be mistaken for cutaneous tcell lymphoma. Chronic actinic dermatitisactinic reticuloid request pdf. Health, general photosensitivity disorders care and treatment case studies diagnosis sezary syndrome. Because cells from pho tosensitivity dermatitis actinic reticuloid patients show in creased sensitivity towards oxidative stress but show no sig nificant change in oxidant activation of the heme oxygenase. The unifying term cad comprises such diseases as persistent light reactions, chronic photosensitivity eczema and actinic reticuloid which have clinical and pathogenetic similarities.
It usually presents as a dermatitis that maximally, but not exclusively, affects photo. Chronic actinic dermatitis cad, also known as the persistent. This article describes two patients suffering from cad with widespread vitiligolike lesions. Actinic keratosis is a scaly spot found on sundamaged skin. Links to pubmed are also available for selected references. Disseminated superficial actinic porokeratosis dsap disseminated superficial actinic porokeratosis.
Chronic actinic dermatitis is a rare skin condition that mainly affects men over the age of 50 years. Actinic reticuloid is a chronic multifactorial dermatitis with severe photosensitivity, which histologically mimics epidermotropic cutaneous tcell lymphoma. It is often treated because it might turn into squamous cell skin cancer. Actinic keratosis is usually considered to be a precancer. Chronic actinic dermatitis is a chronic photodermatosis that occurs most commonly in men in their 60s and 70s. Increasing experience indicates that these syndromes table, which were defined 15 or more years ago and generally occur in elderly men, represent arbitrary, confusing, and largely unnecessary. One of the distressing conditions of actinic reticuloid ar is its persistence for long durations without any demonstrable contact with the phot. Actinic reticuloid definition of actinic reticuloid by.
Actinic keratoses affect people that have often lived in the tropics or subtropics and have predisposing. Diagnosis and treatment of chronic actinic dermatitis request pdf. Chronic actinic dermatitis in the elderly springerlink. May 09, 2017 actinic prurigo ap is a chronic, pruritic skin disease caused by an abnormal reaction to sunlight. Cad is classically thought to be primarily a disease of elderly caucasian males, though recent evidence suggests that in skin of color, the disease manifests more often in younger females.
Actinic definition of actinic by medical dictionary. A 54yearold man suffered from a chronic dermatitis that was more severe on lightexposed areas. Request pdf reticuloide actinico actinic reticuloid is a chronic photodermatosis which is typical of elderly patients and that is characterized by the presence of papules and. The photosensitivity dermatitis and actinic reticuloid syndrome.
Actinic reticuloid ar is a chronic persistent photosensitive dermatosis of elderly men, described first by ive and coworkers in 1969 it is clinically characterized by pruritic infiltrated papules and plaques on exposed parts with occasional extension to covered areas and rarely associated with episodes of erythroderma. Chronic actinic dermatitis cad, one of the immune mediated photodermatoses, comprises a spectrum of. Recalcitrant chronic actinic dermatitis treated with lowdose. Diagnosis is based on clinical, histopathologic, and photobiologic features. Pdf actinic reticuloid presented as facies leonine.
Chronic actinic dermatitis a study of clinical features somani vk. Nuclear contour index helps differentiate actinic reticuloid. Diagnostic criteria were laid down about 20 years back, but clinical features are the mainstay in diagnosis. Chronic actinic dermatitis, synonymous with the photosensitivity dermatitis and actinic reticuloid syndrome, presents as a dermatitis andor a.
Persistent light reactivity, photosensitive eczema, photosensitivity dermatitis, or actinic reticuloid. Actinic reticuloid and actinic granuloma short description. A 52yearold man experienced a pruritic and erythematous eruption on his face, neck, upper chest, and arms. Skin biopsy specimens revealed histopathologic findings. Chronic actinic dermatitis an overview sciencedirect topics. Department of dermatology, free university hospital, amsterdam, netherlands. Apr 10, 2020 chronic actinic dermatitis cad is a photosensitivity disorder defined by a persistent eczematous reaction of 3 months or greater duration on sunexposed body parts, abnormally low phototest. Jul 31, 20 dermatopathology reference describes actinic reticuloid histopathology including histologic features and provides links to additional medical references. Pdf actinic reticuloidphotosensitivity or pseudolymphoma. Differentiation between actinic reticuloid and cutaneous t cell lymphoma by t cell receptor gamma gene rearrangement analysis and immunophenotyping. Clinical report by acta dermatovenerologica alpina, pannonica et adriatica. Actinic reticuloid actinic reticuloid guardiola, armando. The features of this patients disease indicate actinic reticuloid.
Reticuloid definition of reticuloid by medical dictionary. Chronic actinic dermatitis with vitiligolike depigmentation. Chronic actinic dermatitis lesley clarkloeser md dermatology online journal 94. Free full text similar articles actinic reticuloid. Actinic radiation article about actinic radiation by the. Get a printable copy pdf file of the complete article 1. In patients suspected of having actinic reticuloid, application of both techniques.
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